Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Sleep Medicine ClinicsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Genetics of sleep and sleep disorders.Cell. 2011; 146: 194-207
- The economic impact of obstructive sleep apnea.Lung. 2008; 186: 7-12
- The impact of obstructive sleep apnea and daytime sleepiness on work limitation.Sleep Med. 2007; 9: 42-53
- Sleep disorders and work performance: findings from the 2008 National Sleep Foundation Sleep in America poll.J Sleep Res. 2011; 20: 487-494
- The influence of heredity on self-reported sleep patterns in free-living humans.Physiol Behav. 2002; 76: 479-486
- A twin study of sleep duration and body mass index.J Clin Sleep Med. 2010; 6: 11-17
- Vascular endothelial growth factor genotypes and haplotypes contribute to the susceptibility of obstructive sleep apnea syndrome.PLoS One. 2014; 9: e114582
- Functional polymorphisms in the promoter region of MMP-2 and MMP-9 and susceptibility to obstructive sleep apnea.Sci Rep. 2015; 5: 8966
- Heritability of craniofacial structures in normal subjects and patients with sleep apnea.Sleep. 2014; 37: 1689-1698
- The role inflammatory response genes in obstructive sleep apnea syndrome: a review.Sleep Breath. 2015; ([Epub ahead of print])
- Obstructive sleep apnea susceptibility genes in Chinese population: a field synopsis and meta-analysis of genetic association studies.PLoS One. 2015; 10: e0135942
- The CC genotype of the delta-sarcoglycan gene polymorphism rs13170573 is associated with obstructive sleep apnea in the Chinese population.PLoS One. 2014; 9: e114160
- Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea.Genet Mol Res. 2015; 14: 6733-6743
- Molecular signatures of obstructive sleep apnea in adults: a review and perspective.Sleep. 2009; 32: 447-470
- Daytime sympathetic hyperactivity in OSAS is related to excessive daytime sleepiness.J Sleep Res. 2007; 16: 327-332
- Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea.Am J Respir Crit Care Med. 2005; 172: 625-630
- Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy.Am J Respir Crit Care Med. 2000; 162: 566-570
- Refractory hypertension and sleep apnoea: effect of CPAP on blood pressure and baroreflex.Eur Respir J. 2003; 21: 241-247
- Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities.Eur Respir J. 2007; 29: 156-178
- A mediation model linking body weight, cognition, and sleep-disordered breathing.Am J Respir Crit Care Med. 2012; 185: 199-205
- The occurrence of sleep-disordered breathing among middle-aged adults.N Engl J Med. 1993; 328: 1230-1235
- Diagnosis and management of childhood obstructive sleep apnea syndrome.Pediatrics. 2012; 130: 576-584
- Epidemiology of pediatric obstructive sleep apnea.Proc Am Thorac Soc. 2008; 5: 242-252
- Pediatric obstructive sleep apnea and quality of life: a meta-analysis.Otolaryngol Head Neck Surg. 2008; 138: 265-273
- Sleep disordered breathing in children in a general population sample: prevalence and risk factors.Sleep. 2009; 32: 731-736
- Health-related quality of life and depressive symptoms in children with suspected sleep-disordered breathing.Sleep. 2004; 27: 1131-1138
- Prevalence and risk factors for sleep-disordered breathing in 8- to 11-year-old children: association with race and prematurity.J Pediatr. 2003; 142: 383-389
- Obesity and obstructive sleep apnea in children.Paediatr Respir Rev. 2006; 7: 247-259
- Snoring during early childhood and academic performance at ages thirteen to fourteen years.Pediatrics. 2001; 107: 1394-1399
- Pediatric obstructive sleep apnea: complications, management, and long-term outcomes.Proc Am Thorac Soc. 2008; 5: 274-282
- Physiological effects of obstructive sleep apnea syndrome in childhood.Respir Physiol Neurobiol. 2013; 188: 370-382
- Inability of clinical history to distinguish primary snoring from obstructive sleep apnea syndrome in children.Chest. 1995; 108: 610-618
- COUNTERPOINT: does laboratory polysomnography yield better outcomes than home sleep testing? No.Chest. 2015; 148: 308-310
- Algorithm for the diagnosis and treatment of pediatric OSA: a proposal of two pediatric sleep centers.Sleep Med. 2012; 13: 217-227
- Pediatric OSAS: oximetry can provide answers when polysomnography is not available.Sleep Med Rev. 2015; 27: 96-105
- POINT: does laboratory polysomnography yield better outcomes than home sleep testing? Yes.Chest. 2015; 148: 306-308
- Pediatric home sleep apnea testing: slowly getting there!.Chest. 2015; 148: 1382-1395
- Roles of gender, age, race/ethnicity, and residential socioeconomics in obstructive sleep apnea syndromes.Curr Opin Pulm Med. 2012; 18: 568-573
- Cross-cultural comparison of the sleep-disordered breathing prevalence among Americans and Japanese.Eur Respir J. 2010; 36: 379-384
- Impact of sleep apnea on economics.Sleep Med Rev. 2012; 16: 455-462
- Association between obstructive sleep apnea and cancer incidence in a large multicenter Spanish cohort.Am J Respir Crit Care Med. 2013; 187: 99-105
- Symptoms of sleep disordered breathing and risk of cancer: a prospective cohort study.Sleep. 2013; 36: 1429-1435
- Sleep-disordered breathing and cancer mortality: results from the Wisconsin Sleep Cohort Study.Am J Respir Crit Care Med. 2012; 186: 190-194
- Use and cost of health services among overweight and obese Canadian children.Int J Pediatr Obes. 2011; 6: 142-148
- The economic impact of obstructive sleep apnea.Curr Opin Pulm Med. 2013; 19: 639-644
- An official American Thoracic Society statement: continuous positive airway pressure adherence tracking systems. The optimal monitoring strategies and outcome measures in adults.Am J Respir Crit Care Med. 2013; 188: 613-620
- Continuous positive airway pressure treatment of sleepy patients with milder obstructive sleep apnea: results of the CPAP Apnea Trial North American Program (CATNAP) randomized clinical trial.Am J Respir Crit Care Med. 2012; 186: 677-683
- Treatment compliance in patients lost to follow-up after polysomnography.Otolaryngol Head Neck Surg. 2007; 136: 236-240
- Atrial overdrive pacing for the obstructive sleep apnea-hypopnea syndrome.N Engl J Med. 2005; 353: 2568-2577
- Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: a multicenter retrospective study.Am J Respir Crit Care Med. 2010; 182: 676-683
- Diagnosis and management of childhood obstructive sleep apnea syndrome.Pediatrics. 2012; 130: e714-e755
- Novel pharmacological approaches for treatment of obstructive sleep apnea in children.Expert Opin Investig Drugs. 2013; 22: 71-85
- Serum, urine, and breath-related biomarkers in the diagnosis of obstructive sleep apnea in children: is it for real?.Curr Opin Pulm Med. 2012; 18: 561-567
- The human genome diversity project: past, present and future.Nat Rev Genet. 2005; 6: 333-340
- Sequencing technologies—the next generation.Nat Rev Genet. 2010; 11: 31-46
- RNA sequencing: advances, challenges and opportunities.Nat Rev Genet. 2011; 12: 87-98
- Principles and challenges of genomewide DNA methylation analysis.Nat Rev Genet. 2010; 11: 191-203
- ChIP-seq: advantages and challenges of a maturing technology.Nat Rev Genet. 2009; 10: 669-680
- Next-generation proteomics: towards an integrative view of proteome dynamics.Nat Rev Genet. 2013; 14: 35-48
- Metabolomics technology and bioinformatics.Brief Bioinformatics. 2006; 7: 128-139
- Genome-wide gene expression profiling in children with non-obese obstructive sleep apnea.Sleep Med. 2009; 10: 75-86
- Microarray studies of genomic oxidative stress and cell cycle responses in obstructive sleep apnea.Antioxid Redox Signal. 2007; 9: 661-669
- The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool.J Lab Clin Med. 2006; 147: 126-132
- Evaluating the comparability of gene expression in blood and brain.Am J Med Genet B Neuropsychiatr Genet. 2006; 141: 261-268
- Peripheral blood leukocyte gene expression patterns and metabolic parameters in habitually snoring and non-snoring children with normal polysomnographic findings.Sleep. 2011; 34: 153-160
- The promise of translational and personalised approaches for paediatric obstructive sleep apnoea: an 'Omics' perspective.Thorax. 2014; 69: 474-480
- Systemic inflammation in non-obese children with obstructive sleep apnea.Sleep Med. 2007; 9: 254-259
- Plasma C-reactive protein levels among children with sleep-disordered breathing.Pediatrics. 2004; 113: e564-e569
- Transcriptomic analysis identifies phosphatases as novel targets for adenotonsillar hypertrophy of pediatric obstructive sleep apnea.Am J Respir Crit Care Med. 2010; 181: 1114-1120
- Gene expression profiles in peripheral blood mononuclear cells of Asian obstructive sleep apnea patients.Biomed J. 2014; 37: 60-70
- A pathway-based analysis on the effects of obstructive sleep apnea in modulating visceral fat transcriptome.Sleep. 2013; 36: 23-30
- Symptoms of insomnia among patients with obstructive sleep apnea before and after two years of positive airway pressure treatment.Sleep. 2013; 36: 1901-1909
- C-reactive protein, obstructive sleep apnea, and cognitive dysfunction in school-aged children.Am J Respir Crit Care Med. 2007; 176: 188-193
- Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations.Sleep Med. 2014; 15: 228-235
- An integrative model of physiological traits can be used to predict obstructive sleep apnea and response to non positive airway pressure therapy.Sleep. 2015; 38: 961-970
- MicroRNAs: genomics, biogenesis, mechanism, and function.Cell. 2004; 116: 281-297
- Serum microRNAs are promising novel biomarkers.PLoS One. 2008; 3: e3148
- Circulating microRNAs as stable blood-based markers for cancer detection.Proc Natl Acad Sci U S A. 2008; 105: 10513-10518
- MicroRNAs: a new class of regulatory genes affecting metabolism.Cell Metab. 2006; 4: 9-12
- MicroRNAs and heart failure diagnosis: MiR-acle or MiR-age?.Circ Res. 2010; 106: 1011-1013
- The microRNA spectrum in 12 body fluids.Clin Chem. 2010; 56: 1733-1741
- Profiling of circulating microRNAs: from single biomarkers to re-wired networks.Cardiovasc Res. 2012; 93: 555-562
- Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes.Circ Res. 2010; 107: 810-817
- Circulating microRNAs as potential biomarkers of coronary artery disease: a promise to be fulfilled?.Circ Res. 2010; 107: 573-574
- Targeting the circulating microRNA signature of obesity.Clin Chem. 2013; 59: 781-792
- Circulating microRNAs are new and sensitive biomarkers of myocardial infarction.Eur Heart J. 2010; 31: 2765-2773
- Exosomal miRNAs as potential biomarkers of cardiovascular risk in children.J Transl Med. 2014; 12: 162
- microRNAs as peripheral blood biomarkers of cardiovascular disease.Vascul Pharmacol. 2011; 55: 111-118
- Circulating miRNAs as potential biomarkers of endothelial dysfunction in obese children.Chest. 2015; ([Epub ahead of print])
- Precision medicine in patients with resistant hypertension and obstructive sleep apnea: blood pressure response to continuous positive airway pressure treatment.J Am Coll Cardiol. 2015; 66: 1023-1032
- Morphology and topography of nucleus ambiguus projections to cardiac ganglia in rats and mice.Neuroscience. 2007; 149: 845-860
- 8c.08: continuous positive airway pressure is efficient to decrease blood pressure in patients with resistant hypertension. Results from the RHOOSAS study.J Hypertens. 2015; 33: e112
- Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial.JAMA. 2012; 307: 2161-2168
- Sleep apnea: an underestimated cause of resistant hypertension.Curr Hypertens Rev. 2014; 10: 2-7
- Avoidable burden of illness: how much can prevention contribute to health?.Soc Sci Med. 1987; 24: 945-951
- Effects of continuous positive airway pressure on blood pressure in patients with resistant hypertension and obstructive sleep apnea: a meta-analysis.J Hypertens. 2014; 32 ([discussion: 2350]): 2341-2350
- Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial.JAMA. 2013; 310: 2407-2415
- Prevalence and associated factors of obstructive sleep apnea in patients with resistant hypertension.Am J Hypertens. 2014; 27: 1069-1078
- Effects of OSA treatment on BP in patients with resistant hypertension: a randomized trial.Chest. 2013; 144: 1487-1494
- Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism.Chest. 2013; 143: 978-983
- Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.Nat Cell Biol. 2007; 9: 654-659
- Association of severe obstructive sleep apnea and elevated blood pressure despite antihypertensive medication use.J Clin Sleep Med. 2014; 10: 835-843
- A haplotype map of the human genome.Nature. 2005; 437: 1299-1320
- A second generation human haplotype map of over 3.1 million SNPs.Nature. 2007; 449: 851-861
- Fatty-acid binding protein 4 gene variants and childhood obesity: potential implications for insulin sensitivity and CRP levels.Lipids Health Dis. 2010; 9: 18
- Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea.Sleep Med. 2011; 12: 666-671
- Macrophage migration inhibitory factor in cardiovascular disease.Circulation. 2008; 117: 1594-1602
- Macrophage migration inhibitory factor gene polymorphisms and plasma levels in children with obstructive sleep apnea.Pediatr Pulmonol. 2012; 47: 1001-1011
- C-reactive protein and carotid intima-media thickness in children with sleep disordered breathing.J Clin Sleep Med. 2013; 9: 493-498
- Effect of adenotonsillectomy on C-reactive protein levels in children with obstructive sleep apnea: a meta-analysis.Sleep Med. 2013; 14: 172-176
- Morning levels of C-reactive protein in children with obstructive sleep-disordered breathing.Am J Respir Crit Care Med. 2005; 171: 282-286
- Sleep-disordered breathing and C-reactive protein in obese children and adolescents.Sleep Breath. 2014; 18: 335-340
- Obesity and excessive daytime sleepiness in prepubertal children with obstructive sleep apnea.Pediatrics. 2009; 123: 13-18
- Objective sleepiness measures in pediatric obstructive sleep apnea.Pediatrics. 2001; 108: 693-697
- Sleep measures and morning plasma TNF-alpha levels in children with sleep-disordered breathing.Sleep. 2010; 33: 319-325
- TNF-alpha gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea.J Pediatr. 2011; 158: 77-82
- A candidate gene study of obstructive sleep apnea in European Americans and African Americans.Am J Respir Crit Care Med. 2010; 182: 947-953
- Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy.Circulation. 2007; 116: 2307-2314
- Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea.Chest. 2012; 141: 682-691
- Genetic variance in nitric oxide synthase and endothelin genes among children with and without endothelial dysfunction.J Transl Med. 2013; 11: 227
- Polymorphisms in nitric oxide synthase and endothelin genes among children with obstructive sleep apnea.BMC Med Genomics. 2013; 6: 29
- Tumour necrosis factor-alpha (-308) gene polymorphism in obstructive sleep apnoea-hypopnoea syndrome.Eur Respir J. 2005; 26: 673-678
- Reactive oxygen species and the brain in sleep apnea.Respir Physiol Neurobiol. 2010; 174: 307-316
- Cognitive function in prepubertal children with obstructive sleep apnea: a modifying role for NADPH oxidase p22 subunit gene polymorphisms?.Antioxid Redox Signal. 2012; 16: 171-177
- Epigenetic mechanisms that underpin metabolic and cardiovascular diseases.Nat Rev Endocrinol. 2009; 5: 401-408
- Nuclear organization of the genome and the potential for gene regulation.Nature. 2007; 447: 413-417
- Transcription and RNA interference in the formation of heterochromatin.Nature. 2007; 447: 399-406
- Translating the histone code.Science. 2001; 293: 1074-1080
- Cancer epigenomics: beyond genomics.Curr Opin Genet Dev. 2012; 22: 50-55
- Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene.Chest. 2013; 143: 971-977
- DNA methylation in inflammatory genes among children with obstructive sleep apnea.Am J Respir Crit Care Med. 2012; 185: 330-338
- T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea.PLoS One. 2013; 8: e69710
- Alterations in circulating T-cell lymphocyte populations in children with obstructive sleep apnea.Sleep. 2013; 36: 913-922
- Epigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation.Int J Obes. 2015; 39: 1135-1142
- Sex dimorphism in late gestational sleep fragmentation and metabolic dysfunction in offspring mice.Sleep. 2015; 38: 545-557
- Sleep fragmentation during late gestation induces metabolic perturbations and epigenetic changes in adiponectin gene expression in male adult offspring mice.Diabetes. 2014; 63: 3230-3241
- Early-life physical activity reverses metabolic and Foxo1 epigenetic misregulation induced by gestational sleep disturbance.Am J Physiol Regul Integr Comp Physiol. 2015; 308: R419-R430
- Pediatric obstructive sleep apnea and the critical role of oral-facial growth: evidences.Front Neurol. 2012; 3: 184
- Former preterm infants, caffeine was good for you, but now beware of snoring!.Am J Respir Crit Care Med. 2014; 190: 720-721
- Obstructive sleep apnea in the formerly preterm infant: an overlooked diagnosis.Front Neurol. 2011; 2: 73
- Proteome and proteomics: new technologies, new concepts, and new words.Electrophoresis. 1998; 19: 1853-1861
- Proteomics: quantitative and physical mapping of cellular proteins.Trends Biotechnol. 1999; 17: 121-127
- Serum proteomic patterns associated with sleep-disordered breathing in children.Pediatr Res. 2006; 59: 466-470
- Relationship of oxidative stress and endothelial dysfunction in sleep apnoea.Eur Respir J. 2011; 37: 873-879
- Serum proteomic changes in adults with obstructive sleep apnoea.J Sleep Res. 2012; 21: 139-146
- Urinary protein expression patterns in children with sleep-disordered breathing: preliminary findings.Sleep Med. 2006; 7: 221-227
- Two-dimensional differential in-gel electrophoresis proteomic approaches reveal urine candidate biomarkers in pediatric obstructive sleep apnea.Am J Respir Crit Care Med. 2009; 180: 1253-1261
- Contextualised urinary biomarker analysis facilitates diagnosis of paediatric obstructive sleep apnoea.Sleep Med. 2014; 15: 541-549
- Urinary neurotransmitters are selectively altered in children with obstructive sleep apnea and predict cognitive morbidity.Chest. 2013; 143: 1576-1583
- Overview of proteomics studies in obstructive sleep apnea.Sleep Med. 2015; 16: 437-445
Article info
Publication history
Published online: March 02, 2016
Footnotes
Disclosure Statement: No conflicts of interest to declare.
Funding Sources: D. Gozal is supported by the Herbert T. Abelson Endowed Chair in Pediatrics.
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.