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Outcomes from the Tucson Children's Assessment of Sleep Apnea Study

  • Rohit Budhiraja
    Affiliations
    Section of Pulmonary and Critical Care Medicine, Southern Arizona VA Healthcare System and University of Arizona College of Medicine, 3601 South 6th Avenue, Tucson, AZ 85723, USA
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  • Stuart F. Quan
    Correspondence
    Corresponding author. Division of Sleep Medicine, Harvard Medical School, 401 Park Drive, 2nd Floor East, Boston, MA 02215.
    Affiliations
    Department of Medicine, Arizona Respiratory Center, University of Arizona College of Medicine, 1501 N. Campbell Avenue, Tucson, AZ 85724, USA

    Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, 401 Park Drive, 2nd Floor East, Boston, MA 02215, USA
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      Sleep-disordered breathing (SDB) is increasingly recognized as an important clinical problem in children; however, the clinical, anatomic, and physiologic correlates of SDB have not been studied extensively in a general population sample using polysomnography to document the presence of SDB. The Tucson Children's Assessment of Sleep Apnea Study is a longitudinal cohort study of 503 Caucasian and Hispanic children aged 6 to 12 years old who underwent polysomnography and neurocognitive testing at the time of recruitment. Subsets of the cohort had additional MR imaging and pulmonary physiologic testing. Initial cross-sectional analyses indicate that SDB is associated with behavioral abnormalities, hypertension, learning problems, and clinical symptoms such as snoring and excessive daytime sleepiness. Future follow-up of the cohort will assess the impact of SDB on subsequent childhood development.

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